Publications

At Eckerd

1. Tarhan AK, Feng Z, Fernandez D, Kim AYJ, Bearrood TE, Hinman A, White NR, Chen JK. “Development of next-generation ALDH1B1 inhibitors with enhanced pharmacological and functional properties” ChemRxiv. 2025; doi:10.26434/chemrxiv-2025-9cq5c. *This content is a preprint and has not been peer-reviewed. article

Before Eckerd

4. Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernández D, Ondrus AE, McCormick AK, Tomaske MG, Gu Y, Marshall CR, Kline T, Chen C, Mochly-Rosen D, Kuo CJ, Chen JK. “Targeting colorectal cancer with small-molecule inhibitors of aldehyde dehydrogenase 1B1” Nature Chemical Biology. 2022. 18. 1065-1075. article

3. Bearrood TE, Aguirre-Figueroa G, Chan J. “Rational Design of a Red Fluorescent Sensor for ALDH1A1 Displaying Enhanced Cellular Uptake and Reactivity” Molecular Imaging Special Edition (invited). Bioconjugate Chemistry. 2020. 31. 224-228. article

2. Anorma C,* Hedhli J,* Bearrood TE,* Pino NW, Gardner SH, Inaba H, Zhang P, Li Y, Feng D, Dibrell SE, Kilian KA, Dobrucki LW, Fan TM, Chan J. “Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1” ACS Central Science. 2018. 4. 1045-1055. (* denotes equal contribution) article

1. Bearrood TE, Chan J. “Disproportionate Impact of Named Reactions on Chemical Biology” Aldrichimica Acta. 2017. 50. 31-42. article